Nature-inspired topographies on hydroxyapatite surfaces regulate stem cells behaviour
نویسندگان
چکیده
منابع مشابه
Cell Adhesion On Surfaces Of Varying Topographies
Micro-topography of a surface in?uences cell adhesion and proliferation. To improve adhesion, polyelectrolyte multilay ers (PEMs) are built on patterned support layers to increase surface Wettability, thereby improving attachment and spreading of the cells. Physical parameters, such as pattern siZe and pitch, in part, regulate cell adhesion and prolifera tion. Varying the surface topography pro...
متن کاملOsteogenesis of bone marrow mesenchymal stem cells on strontium-substituted nano-hydroxyapatite coated roughened titanium surfaces.
OBJECTIVE To investigate osteogenesis of bone marrow mesenchymal stem cells (BMSCs) on strontium-substituted nano-hydroxyapatite (Sr-HA) coated roughened titanium surfaces. METHODS Sr-HA coating and HA coating were fabricated on roughened titanium surfaces by electrochemical deposition technique and characterized by field emission scanning electron microscope (FESM). BMSCs were cultured on Sr...
متن کاملMicro- and Nanoscale Topographies on Silk Regulate Gene Expression of Human Corneal Epithelial Cells
Purpose Corneal basement membrane has topographical features that provide biophysical cues to direct cell adherence, migration, and proliferation. In this study, we hypothesize that varying topographic pitch created on silk films can alter epithelial cell morphology, adhesion, and the genetic expression involved in cytoskeletal dynamics-related pathways. Methods Silicon wafers with parallel r...
متن کاملGenomic expression of mesenchymal stem cells to altered nanoscale topographies.
The understanding of cellular response to the shape of their environment would be of benefit in the development of artificial extracellular environments for potential use in the production of biomimetic surfaces. Specifically, the understanding of how cues from the extracellular environment can be used to understand stem cell differentiation would be of special interest in regenerative medicine...
متن کاملWettability influences cell behavior on superhydrophobic surfaces with different topographies.
Surface wettability and topography are recognized as critical factors influencing cell behavior on biomaterials. So far only few works have reported cell responses on surfaces exhibiting extreme wettability in combination with surface topography. The goal of this work is to study whether cell behavior on superhydrophobic surfaces is influenced by surface topography and polymer type. Biomimetic ...
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ژورنال
عنوان ژورنال: Bioactive Materials
سال: 2021
ISSN: 2452-199X
DOI: 10.1016/j.bioactmat.2020.10.001